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A universal glycoenzyme biosynthesis pipeline that enables efficient cell-free remodeling of glycans

The ability to reconstitute natural glycosylation pathways or prototype entirely new ones from scratch is hampered by the limited availability of functional glycoenzymes, many of which are membrane proteins that fail to express in heterologous hosts. Here, we describe a strategy for topologically co...

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Detalles Bibliográficos
Autores principales: Jaroentomeechai, Thapakorn, Kwon, Yong Hyun, Liu, Yiwen, Young, Olivia, Bhawal, Ruchika, Wilson, Joshua D., Li, Mingji, Chapla, Digantkumar G., Moremen, Kelley W., Jewett, Michael C., Mizrachi, Dario, DeLisa, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592599/
https://www.ncbi.nlm.nih.gov/pubmed/36280670
http://dx.doi.org/10.1038/s41467-022-34029-7