Ribosome-mediated biosynthesis of pyridazinone oligomers in vitro

The ribosome is a macromolecular machine that catalyzes the sequence-defined polymerization of L-α-amino acids into polypeptides. The catalysis of peptide bond formation between amino acid substrates is based on entropy trapping, wherein the adjacency of transfer RNA (tRNA)-coupled acyl bonds in the...

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Detalles Bibliográficos
Autores principales: Lee, Joongoo, Coronado, Jaime N., Cho, Namjin, Lim, Jongdoo, Hosford, Brandon M., Seo, Sangwon, Kim, Do Soon, Kofman, Camila, Moore, Jeffrey S., Ellington, Andrew D., Anslyn, Eric V., Jewett, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592601/
https://www.ncbi.nlm.nih.gov/pubmed/36280685
http://dx.doi.org/10.1038/s41467-022-33701-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592601/
https://www.ncbi.nlm.nih.gov/pubmed/36280685
http://dx.doi.org/10.1038/s41467-022-33701-2

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