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Ribosome-mediated biosynthesis of pyridazinone oligomers in vitro

The ribosome is a macromolecular machine that catalyzes the sequence-defined polymerization of L-α-amino acids into polypeptides. The catalysis of peptide bond formation between amino acid substrates is based on entropy trapping, wherein the adjacency of transfer RNA (tRNA)-coupled acyl bonds in the...

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Detalles Bibliográficos
Autores principales:	Lee, Joongoo, Coronado, Jaime N., Cho, Namjin, Lim, Jongdoo, Hosford, Brandon M., Seo, Sangwon, Kim, Do Soon, Kofman, Camila, Moore, Jeffrey S., Ellington, Andrew D., Anslyn, Eric V., Jewett, Michael C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592601/ https://www.ncbi.nlm.nih.gov/pubmed/36280685 http://dx.doi.org/10.1038/s41467-022-33701-2

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