Hepatotoxic metabolites in Polygoni Multiflori Radix— Comparative toxicology in mice

Polygoni Multiflori Radix (PM) and Rhei radix et rhizoma (rhubarb) contain similar hepatocyte-toxic anthraquinones such as emodin (major free anthraquinone in PM), physcion and their glycosides. In clinical practice, PM hepatotoxicity has been widely reported, although rhubarb is not recognized as h...

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Detalles Bibliográficos
Autores principales: Wang, Shixiao, Kong, Xiang, Chen, Ning, Hu, Pengwei, Boucetta, Hamza, Hu, Zhaoliang, Xu, Xin, Zhang, Pei, Zhan, Xiang, Chang, Ming, Cheng, Rui, Wu, Wei, Song, Min, Lu, Yuting, Hang, Taijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592908/
https://www.ncbi.nlm.nih.gov/pubmed/36304159
http://dx.doi.org/10.3389/fphar.2022.1007284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592908/
https://www.ncbi.nlm.nih.gov/pubmed/36304159
http://dx.doi.org/10.3389/fphar.2022.1007284

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