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Hepatotoxic metabolites in Polygoni Multiflori Radix— Comparative toxicology in mice
Polygoni Multiflori Radix (PM) and Rhei radix et rhizoma (rhubarb) contain similar hepatocyte-toxic anthraquinones such as emodin (major free anthraquinone in PM), physcion and their glycosides. In clinical practice, PM hepatotoxicity has been widely reported, although rhubarb is not recognized as h...
Autores principales: | Wang, Shixiao, Kong, Xiang, Chen, Ning, Hu, Pengwei, Boucetta, Hamza, Hu, Zhaoliang, Xu, Xin, Zhang, Pei, Zhan, Xiang, Chang, Ming, Cheng, Rui, Wu, Wei, Song, Min, Lu, Yuting, Hang, Taijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592908/ https://www.ncbi.nlm.nih.gov/pubmed/36304159 http://dx.doi.org/10.3389/fphar.2022.1007284 |
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