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Inhibition of angiogenetic macrophages reduces disc degeneration-associated pain

Abnormal angiogenesis and innervation in avascular discs during lumbar disc degeneration (LDD) cause severe back pain. These pathological alterations in the degenerating discs are induced by cytokines partially produced and secreted by inflammatory cells, among which macrophages are the most frequen...

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Detalles Bibliográficos
Autores principales: Hou, Yang, Shi, Jiangang, Guo, Yongfei, Shi, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592909/
https://www.ncbi.nlm.nih.gov/pubmed/36304897
http://dx.doi.org/10.3389/fbioe.2022.962155