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Risk of major adverse events associated with gabapentinoid and opioid combination therapy: A systematic review and meta-analysis
Background: The use of opioid–gabapentinoid combinations has increased, raising several safety concerns. However, meta-analysis studies focusing on this issue are limited. Objective: To evaluate the risk of central nervous system (CNS) depression, gastrointestinal (GI) adverse events, and mortality...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593000/ https://www.ncbi.nlm.nih.gov/pubmed/36304170 http://dx.doi.org/10.3389/fphar.2022.1009950 |