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The extracellular matrix protein fibulin-3/EFEMP1 promotes pleural mesothelioma growth by activation of PI3K/Akt signaling

Malignant pleural mesothelioma (MPM) is an aggressive tumor with poor prognosis and limited therapeutic options. The extracellular matrix protein fibulin-3/EFEMP1 accumulates in the pleural effusions of MPM patients and has been proposed as a prognostic biomarker of these tumors. However, it is enti...

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Detalles Bibliográficos
Autores principales: Roshini, Arivazhagan, Goparaju, Chandra, Kundu, Somanath, Nandhu, Mohan S., Longo, Sharon L., Longo, John A., Chou, Joan, Middleton, Frank A., Pass, Harvey I., Viapiano, Mariano S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593058/
https://www.ncbi.nlm.nih.gov/pubmed/36303838
http://dx.doi.org/10.3389/fonc.2022.1014749