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Microwave-assisted multicomponent synthesis of antiproliferative 2,4-dimethoxy-tetrahydropyrimido[4,5-b]quinolin-6(7H)-ones

In this study, we demonstrate a simple, highly efficient, rapid and convenient series of 2,4-dimethoxy-tetrahydropyrimido[4,5-b]quinolin-6(7H)-ones 4a–v. Microwave irradiation facilitates the one-pot multicomponent reaction of different aromatic aldehydes, 6-amino-2,4-dimethoxypyrimidine and dimedon...

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Detalles Bibliográficos
Autores principales: Patel, Subham G., González-Bakker, Aday, Vala, Ruturajsinh M., Patel, Paras J., Puerta, Adrián, Malik, Apoorva, Sharma, Rakesh K., Padrón, José M., Patel, Hitendra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593171/
https://www.ncbi.nlm.nih.gov/pubmed/36337956
http://dx.doi.org/10.1039/d2ra04669e