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Kinesin-2 motors differentially impact biogenesis of extracellular vesicle subpopulations shed from sensory cilia

Extracellular vesicles (EVs) are bioactive lipid-bilayer enclosed particles released from nearly all cells. One specialized site for EV shedding is the primary cilium. Here, we discover the conserved ion channel CLHM-1 as a ciliary EV cargo. Imaging of EVs released from sensory neuron cilia of Caeno...

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Detalles Bibliográficos
Autores principales: Clupper, Michael, Gill, Rachael, Elsayyid, Malek, Touroutine, Denis, Caplan, Jeffrey L., Tanis, Jessica E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593189/
https://www.ncbi.nlm.nih.gov/pubmed/36304122
http://dx.doi.org/10.1016/j.isci.2022.105262