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In vitro neutrophil migration is associated with inhaled corticosteroid treatment and serum cytokines in pediatric asthma

Background: Different asthma phenotypes are driven by molecular endotypes. A Th1-high phenotype is linked to severe, therapy-refractory asthma, subclinical infections and neutrophil inflammation. Previously, we found neutrophil granulocytes (NGs) from asthmatics exhibit decreased chemotaxis towards...

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Detalles Bibliográficos
Autores principales: Lemmel, Solveig, Weckmann, Markus, Wohlers, Anna, Jirmo, Adan Chari, Grychtol, Ruth, Ricklefs, Isabell, Nissen, Gyde, Bachmann, Anna, Singh, Shantanu, Caicedo, Juan, Bahmer, Thomas, Hansen, Gesine, Von Mutius, Erika, Rabe, Klaus F., Fuchs, Oliver, Dittrich, Anna-Maria, Schaub, Bianca, Happle, Christine, Carpenter, Anne E., Kopp, Matthias Volkmar, Becker, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593213/
https://www.ncbi.nlm.nih.gov/pubmed/36304163
http://dx.doi.org/10.3389/fphar.2022.1021317