Cytoplasmic and mitochondrial aminoacyl-tRNA synthetases differentially regulate lifespan in Caenorhabditis elegans

Reducing the rate of translation promotes longevity in multiple organisms, representing a conserved mechanism for lifespan extension. Aminoacyl-tRNA synthetases (ARSs) catalyze the loading of amino acids to their cognate tRNAs, thereby playing an essential role in translation. Mutations in ARS genes...

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Detalles Bibliográficos
Autores principales: Zheng, Tianlin, Luo, Qiang, Han, Chengxuan, Zhou, Jiejun, Gong, Jianke, Chun, Lei, Xu, X.Z. Shawn, Liu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593246/
https://www.ncbi.nlm.nih.gov/pubmed/36304099
http://dx.doi.org/10.1016/j.isci.2022.105266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593246/
https://www.ncbi.nlm.nih.gov/pubmed/36304099
http://dx.doi.org/10.1016/j.isci.2022.105266

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