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Genomic G-quadruplex folding triggers a cytokine-mediated inflammatory feedback loop to aggravate inflammatory diseases

DNA G-quadruplex is a non-canonical secondary structure that could epigenetically regulate gene expression. To investigate the regulating role of G-quadruplex, we devised an integrating method to perform the algorithm profiling and genome-wide analysis for the dynamic change of genomic G-quadruplex...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolin, Chen, Shunlun, Zhao, Zhuoyang, Chen, Fan, Huang, Yuming, Guo, Xingyu, Lei, Linchuan, Wang, Wantao, Luo, Yanxin, Yu, Huichuan, Wang, Jianru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593248/
https://www.ncbi.nlm.nih.gov/pubmed/36304116
http://dx.doi.org/10.1016/j.isci.2022.105312