NRas activity is regulated by dynamic interactions with nanoscale signaling clusters at the plasma membrane

NRas is a key mediator of the mitogenic pathway in normal cells and in cancer cells. Its dynamics and nanoscale organization at the plasma membrane (PM) facilitate its signaling. Here, we used two-color photoactivated localization microscopy to resolve the organization of individual NRas and associa...

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Detalles Bibliográficos
Autores principales: Yakovian, Oren, Sajman, Julia, Alon, Michal, Arafeh, Rand, Samuels, Yardena, Sherman, Eilon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593252/
https://www.ncbi.nlm.nih.gov/pubmed/36304112
http://dx.doi.org/10.1016/j.isci.2022.105282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593252/
https://www.ncbi.nlm.nih.gov/pubmed/36304112
http://dx.doi.org/10.1016/j.isci.2022.105282

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