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Single-cell transcriptome profiling reveals heterogeneous neutrophils with prognostic values in sepsis

Neutrophils constitute the largest proportion of nucleated peripheral blood cells, and neutrophils have substantial heterogeneity. We profiled nearly 300,000 human peripheral blood cells in this study using single-cell RNA sequencing. A large proportion (>50%) of these cells were annotated as neu...

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Detalles Bibliográficos
Autores principales: Hong, Yucai, Chen, Lin, Sun, Jian, Xing, Lifeng, Yang, Yi, Jin, Xiaohong, Cai, Huabo, Dong, Lianlian, Zhou, Liping, Zhang, Zhongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593767/
https://www.ncbi.nlm.nih.gov/pubmed/36304125
http://dx.doi.org/10.1016/j.isci.2022.105301