CIITA promoter polymorphism impairs monocytes HLA-DR expression in patients with septic shock

Low monocyte (m)HLA-DR expression is associated with mortality in sepsis. G-286A∗rs3087456 polymorphism in promoter III of HLA class II transactivator (CIITA), the master regulator of HLA, has been associated with autoimmune diseases but its role in sepsis has never been demonstrated. In 203 patient...

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Detalles Bibliográficos
Autores principales: Miatello, Jordi, Lukaszewicz, Anne-Claire, Carter, Michael J., Faivre, Valérie, Hua, Stéphane, Martinet, Kim Z., Bourgeois, Christine, Quintana-Murci, Lluis, Payen, Didier, Boniotto, Michele, Tissières, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593818/
https://www.ncbi.nlm.nih.gov/pubmed/36304101
http://dx.doi.org/10.1016/j.isci.2022.105291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593818/
https://www.ncbi.nlm.nih.gov/pubmed/36304101
http://dx.doi.org/10.1016/j.isci.2022.105291

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