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Lipid hydroperoxides and oxylipins are mediators of denervation induced muscle atrophy
Loss of innervation is a key driver of age associated muscle atrophy and weakness (sarcopenia). Our laboratory has previously shown that denervation induced atrophy is associated with the generation of mitochondrial hydroperoxides and lipid mediators produced downstream of cPLA(2) and 12/15 lipoxyge...
Autores principales: | Brown, Jacob L., Peelor, Fredrick F., Georgescu, Constantin, Wren, Jonathan D., Kinter, Michael, Tyrrell, Victoria J., O'Donnell, Valerie B., Miller, Benjamin F., Van Remmen, Holly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593840/ https://www.ncbi.nlm.nih.gov/pubmed/36283174 http://dx.doi.org/10.1016/j.redox.2022.102518 |
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