SUMMIT: An integrative approach for better transcriptomic data imputation improves causal gene identification

Genes with moderate to low expression heritability may explain a large proportion of complex trait etiology, but such genes cannot be sufficiently captured in conventional transcriptome-wide association studies (TWASs), partly due to the relatively small available reference datasets for developing e...

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Detalles Bibliográficos
Autores principales: Zhang, Zichen, Bae, Ye Eun, Bradley, Jonathan R., Wu, Lang, Wu, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593997/
https://www.ncbi.nlm.nih.gov/pubmed/36284135
http://dx.doi.org/10.1038/s41467-022-34016-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9593997/
https://www.ncbi.nlm.nih.gov/pubmed/36284135
http://dx.doi.org/10.1038/s41467-022-34016-y

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