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Coupled Natural Fusion Enzymes in a Novel Biocatalytic Cascade Convert Fatty Acids to Amines

[Image: see text] Tambjamine YP1 is a pyrrole-containing natural product. Analysis of the enzymes encoded in the Pseudoalteromonas tunicata “tam” biosynthetic gene cluster (BGC) identified a unique di-domain biocatalyst (PtTamH). Sequence and bioinformatic analysis predicts that PtTamH comprises an...

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Detalles Bibliográficos
Autores principales: Richardson, Shona M., Marchetti, Piera M., Herrera, Michael A., Campopiano, Dominic J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594044/
https://www.ncbi.nlm.nih.gov/pubmed/36313522
http://dx.doi.org/10.1021/acscatal.2c02954