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Coupled Natural Fusion Enzymes in a Novel Biocatalytic Cascade Convert Fatty Acids to Amines
[Image: see text] Tambjamine YP1 is a pyrrole-containing natural product. Analysis of the enzymes encoded in the Pseudoalteromonas tunicata “tam” biosynthetic gene cluster (BGC) identified a unique di-domain biocatalyst (PtTamH). Sequence and bioinformatic analysis predicts that PtTamH comprises an...
Autores principales: | Richardson, Shona M., Marchetti, Piera M., Herrera, Michael A., Campopiano, Dominic J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594044/ https://www.ncbi.nlm.nih.gov/pubmed/36313522 http://dx.doi.org/10.1021/acscatal.2c02954 |
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