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Potentially Prebiotic Activation Chemistry Compatible with Nonenzymatic RNA Copying

[Image: see text] The nonenzymatic replication of ribonucleic acid (RNA) may have enabled the propagation of genetic information during the origin of life. RNA copying can be initiated in the laboratory with chemically activated nucleotides, but continued copying requires a source of chemical energy...

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Detalles Bibliográficos
Autores principales: Zhang, Stephanie J., Duzdevich, Daniel, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594304/
https://www.ncbi.nlm.nih.gov/pubmed/32794700
http://dx.doi.org/10.1021/jacs.0c05300