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Analysis of Slow-Cycling Variants of the Light-Inducible Nuclear Protein Export System LEXY in Mammalian Cells

[Image: see text] The optogenetic tool LEXY consists of the second light oxygen voltage (LOV) domain of Avena sativa phototropin 1 mutated to contain a nuclear export signal. It allows exporting from the nucleus with blue light proteins of interest (POIs) genetically fused to it. Mutations slowing t...

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Detalles Bibliográficos
Autores principales: Forlani, Giada, Antwi, Enoch B., Weis, Daniel, Öztürk, Mehmet A., Queck, Bastian A.W., Brecht, Dominik, Di Ventura, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594308/
https://www.ncbi.nlm.nih.gov/pubmed/36180042
http://dx.doi.org/10.1021/acssynbio.2c00232