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Induced CD45 Proximity Potentiates Natural Killer Cell Receptor Antagonism

[Image: see text] Natural killer (NK) cells are a major subset of innate immune cells that are essential for host defense against pathogens and cancer. Two main classes of inhibitory NK receptors (NKR), KIR and CD94/NKG2A, play a key role in suppressing NK activity upon engagement with tumor cells o...

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Detalles Bibliográficos
Autores principales: Ren, Junming, Jo, Yeara, Picton, Lora K., Su, Leon L., Raulet, David H., Garcia, K. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594326/
https://www.ncbi.nlm.nih.gov/pubmed/36169352
http://dx.doi.org/10.1021/acssynbio.2c00337