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Solid-Phase Synthesis of Sequence-Defined Informational Oligomers

[Image: see text] Genetic biopolymers utilize defined sequences and monomer-specific molecular recognition to store and transfer information. Synthetic polymers that mimic these attributes using reversible covalent chemistry for base-pairing pose unique synthetic challenges. Here, we describe a soli...

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Detalles Bibliográficos
Autores principales: Strom, Kyle R., Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594334/
https://www.ncbi.nlm.nih.gov/pubmed/33064001
http://dx.doi.org/10.1021/acs.joc.0c01977