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Quantification of Genome Editing and Transcriptional Control Capabilities Reveals Hierarchies among Diverse CRISPR/Cas Systems in Human Cells

[Image: see text] CRISPR/Cas technologies have revolutionized the ability to redesign genomic information and tailor endogenous gene expression. Nevertheless, the discovery and development of new CRISPR/Cas systems has resulted in a lack of clarity surrounding the relative efficacies among these tec...

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Detalles Bibliográficos
Autores principales: Escobar, Mario, Li, Jing, Patel, Aditi, Liu, Shizhe, Xu, Qi, Hilton, Isaac B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594343/
https://www.ncbi.nlm.nih.gov/pubmed/36162812
http://dx.doi.org/10.1021/acssynbio.2c00156