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Combining precision oncology and immunotherapy by targeting the MALT1 protease

An innovative strategy for cancer therapy is to combine the inhibition of cancer cell-intrinsic oncogenic signaling with cancer cell-extrinsic immunological activation of the tumor microenvironment (TME). In general, such approaches will focus on two or more distinct molecular targets in the maligna...

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Detalles Bibliográficos
Autores principales: Mempel, Thorsten R, Krappmann, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594517/
https://www.ncbi.nlm.nih.gov/pubmed/36270731
http://dx.doi.org/10.1136/jitc-2022-005442