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Free water derived by multi‐shell diffusion MRI reflects tau/neuroinflammatory pathology in Alzheimer's disease

INTRODUCTION: Free‐water (FW) imaging, a new analysis method for diffusion magnetic resonance imaging (MRI), can indicate neuroinflammation and degeneration. We evaluated FW in Alzheimer's disease (AD) using tau/inflammatory and amyloid positron emission tomography (PET). METHODS: Seventy‐one p...

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Detalles Bibliográficos
Autores principales: Nakaya, Moto, Sato, Noriko, Matsuda, Hiroshi, Maikusa, Norihide, Shigemoto, Yoko, Sone, Daichi, Yamao, Tensho, Ogawa, Masayo, Kimura, Yukio, Chiba, Emiko, Ohnishi, Masahiro, Kato, Koichi, Okita, Kyoji, Tsukamoto, Tadashi, Yokoi, Yuma, Sakata, Masuhiro, Abe, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594557/
https://www.ncbi.nlm.nih.gov/pubmed/36304723
http://dx.doi.org/10.1002/trc2.12356