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Radiological evolution of spinal disease in alkaptonuria and the effect of nitisinone

OBJECTIVES: Ochronotic spondyloarthropathy represents one of the main clinical manifestations of alkaptonuria (AKU); however, prospective data and description of the effect of nitisinone treatment are lacking. METHODS: Patients with AKU aged 25 years or older were randomly assigned to receive either...

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Detalles Bibliográficos
Autores principales: Imrich, Richard, Sedláková, Jana, Úlehlová, Mária, Gornall, Matthew, Jackson, Richard, Olsson, Birgitta, Rudebeck, Mattias, Gallagher, James, Lukáčová, Oľga, Mlynáriková, Vanda, Stančík, Roman, Vrtíková, Eva, Záňová, Elizabeth, Zaťková, Andrea, Arnoux, Jean-Baptiste, Rovenský, Jozef, Luangrath, Emily, Bygott, Helen, Khedr, Milad, Ranganath, Lakshminarayan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594597/
https://www.ncbi.nlm.nih.gov/pubmed/36270742
http://dx.doi.org/10.1136/rmdopen-2022-002422