Cargando…

Functional Comparison between Endogenous and Synthetic Notch Systems

[Image: see text] The Notch pathway converts receptor–ligand interactions at the cell surface into a transcriptional response in the receiver cell. In recent years, synthetic Notch systems (synNotch) that respond to different inputs and transduce different transcriptional responses have been enginee...

Descripción completa

Detalles Bibliográficos
Autores principales: Khamaisi, Bassma, Luca, Vincent C., Blacklow, Stephen C., Sprinzak, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594772/
https://www.ncbi.nlm.nih.gov/pubmed/36107643
http://dx.doi.org/10.1021/acssynbio.2c00247