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LncRNA FENDRR with m6A RNA methylation regulates hypoxia-induced pulmonary artery endothelial cell pyroptosis by mediating DRP1 DNA methylation

BACKGROUND: Pyroptosis is a form of programmed cell death involved in the pathophysiological progression of hypoxic pulmonary hypertension (HPH). Emerging evidence suggests that N6-methyladenosine (m6A)-modified transcripts of long noncoding RNAs (lncRNAs) are important regulators that participate i...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoying, Li, Qian, He, Siyu, Bai, June, Ma, Cui, Zhang, Lixin, Guan, Xiaoyu, Yuan, Hao, Li, Yiying, Zhu, Xiangrui, Mei, Jian, Gao, Feng, Zhu, Daling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594874/
https://www.ncbi.nlm.nih.gov/pubmed/36284300
http://dx.doi.org/10.1186/s10020-022-00551-z