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B3GALT4 remodels the tumor microenvironment through GD2-mediated lipid raft formation and the c-met/AKT/mTOR/IRF-1 axis in neuroblastoma

BACKGROUND: Beta-1,3-galactosyltransferase-4 (B3GALT4) plays a critical regulatory role in tumor biology. However, the role of B3GALT4 in modulating the tumor microenvironment (TME) of neuroblastoma (NB) remains unknown. METHODS: Public datasets and clinical NB samples were collected to evaluate the...

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Detalles Bibliográficos
Autores principales: Sha, Yong-Liang, Liu, Yun, Yang, Jia-Xing, Wang, Yang-Yang, Gong, Bao-Cheng, Jin, Yan, Qu, Tong-Yuan, Xia, Fan-Tong, Han, Lei, Zhao, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594894/
https://www.ncbi.nlm.nih.gov/pubmed/36284313
http://dx.doi.org/10.1186/s13046-022-02523-x