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B3GALT4 remodels the tumor microenvironment through GD2-mediated lipid raft formation and the c-met/AKT/mTOR/IRF-1 axis in neuroblastoma
BACKGROUND: Beta-1,3-galactosyltransferase-4 (B3GALT4) plays a critical regulatory role in tumor biology. However, the role of B3GALT4 in modulating the tumor microenvironment (TME) of neuroblastoma (NB) remains unknown. METHODS: Public datasets and clinical NB samples were collected to evaluate the...
Autores principales: | Sha, Yong-Liang, Liu, Yun, Yang, Jia-Xing, Wang, Yang-Yang, Gong, Bao-Cheng, Jin, Yan, Qu, Tong-Yuan, Xia, Fan-Tong, Han, Lei, Zhao, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594894/ https://www.ncbi.nlm.nih.gov/pubmed/36284313 http://dx.doi.org/10.1186/s13046-022-02523-x |
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