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Angiotensin-converting enzyme 2 identifies immuno-hot tumors suggesting angiotensin-(1–7) as a sensitizer for chemotherapy and immunotherapy in breast cancer

BACKGROUND: Angiotensin-converting enzyme 2 (ACE2) is known as a tumor suppressor and lowly expressed in most cancers. The expression pattern and role of ACE2 in breast cancer (BC) have not been deeply elucidated. METHODS: A systematic pan-cancer analysis was conducted to assess the expression patte...

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Detalles Bibliográficos
Autores principales: Mei, Jie, Cai, Yun, Xu, Rui, Yu, Xinqian, Han, Xu, Weng, Miaomiao, Chen, Lingyan, Ma, Tao, Gao, Tianshu, Gao, Fei, Xia, Tiansong, Zhu, Yichao, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594906/
https://www.ncbi.nlm.nih.gov/pubmed/36284262
http://dx.doi.org/10.1186/s12575-022-00177-9