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ReadZS detects cell type-specific and developmentally regulated RNA processing programs in single-cell RNA-seq
RNA processing, including splicing and alternative polyadenylation, is crucial to gene function and regulation, but methods to detect RNA processing from single-cell RNA sequencing data are limited by reliance on pre-existing annotations, peak calling heuristics, and collapsing measurements by cell...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594907/ https://www.ncbi.nlm.nih.gov/pubmed/36284317 http://dx.doi.org/10.1186/s13059-022-02795-8 |