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ReadZS detects cell type-specific and developmentally regulated RNA processing programs in single-cell RNA-seq

RNA processing, including splicing and alternative polyadenylation, is crucial to gene function and regulation, but methods to detect RNA processing from single-cell RNA sequencing data are limited by reliance on pre-existing annotations, peak calling heuristics, and collapsing measurements by cell...

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Detalles Bibliográficos
Autores principales:	Meyer, Elisabeth, Chaung, Kaitlin, Dehghannasiri, Roozbeh, Salzman, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594907/ https://www.ncbi.nlm.nih.gov/pubmed/36284317 http://dx.doi.org/10.1186/s13059-022-02795-8

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