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An Effective Glucagon-Like Peptide-1 Receptor Agonists, Semaglutide, Improves Sarcopenic Obesity in Obese Mice by Modulating Skeletal Muscle Metabolism

PURPOSE: This study aimed to investigate the effect of Semaglutide on skeletal muscle and its metabolomics. METHODS: A total of 18 male C57BL/6 mice were randomly divided into normal control (NC) group, high-fat diet (HFD) group and HFD+Semaglutide group, and were given standard diet, HFD diet, HFD...

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Detalles Bibliográficos
Autores principales: Ren, Qingjuan, Chen, Shuchun, Chen, Xing, Niu, Shu, Yue, Lin, Pan, Xiaoyu, Li, Zelin, Chen, Xiaoyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9594960/
https://www.ncbi.nlm.nih.gov/pubmed/36304787
http://dx.doi.org/10.2147/DDDT.S381546