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Construction of an rAAV Producer Cell Line through Synthetic Biology

[Image: see text] Recombinant adeno-associated viruses (rAAV) are important gene delivery vehicles for gene therapy applications. Their production relies on plasmid transfection or virus infection of producer cells, which pose a challenge in process scale-up. Here, we describe a template for a trans...

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Detalles Bibliográficos
Autores principales: Lee, Zion, Lu, Min, Irfanullah, Eesha, Soukup, Morgan, Hu, Wei-Shou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595119/
https://www.ncbi.nlm.nih.gov/pubmed/36219557
http://dx.doi.org/10.1021/acssynbio.2c00207