Cargando…

Apoptosis-associated speck-like protein containing a CARD-mediated release of matrix metalloproteinase 10 stimulates a change in microglia phenotype

Inflammation contributes to amyloid-β and tau pathology in Alzheimer’s disease (AD). Microglia facilitate an altered immune response that includes microgliosis, upregulation of inflammasome proteins, and elevation of matrix-metalloproteinases (MMPs). Studies of cerebrospinal fluid (CSF) and blood in...

Descripción completa

Detalles Bibliográficos
Autores principales: Sánchez, Kathryn E., Bhaskar, Kiran, Rosenberg, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595131/
https://www.ncbi.nlm.nih.gov/pubmed/36305000
http://dx.doi.org/10.3389/fnmol.2022.976108