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Co‐Anchoring of Engineered Immunogen and Immunostimulatory Cytokines to Alum Promotes Enhanced‐Humoral Immunity

Protein antigens are often combined with aluminum hydroxide (alum), the most commonly used adjuvant in licensed vaccines; yet the immunogenicity of alum‐adjuvanted vaccines leaves much room for improvement. Here, the authors demonstrate a strategy for codelivering an immunostimulatory cytokine, the...

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Detalles Bibliográficos
Autores principales: Chang, Jason Y. H., Agarwal, Yash, Rodrigues, Kristen A., Momin, Noor, Ni, Kaiyuan, Read, Benjamin J., Moyer, Tyson J., Mehta, Naveen K., Silva, Murillo, Suh, Heikyung, Melo, Mariane B., Wittrup, K. Dane, Irvine, Darrell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595138/
https://www.ncbi.nlm.nih.gov/pubmed/36311814
http://dx.doi.org/10.1002/adtp.202100235