Cargando…
Co‐Anchoring of Engineered Immunogen and Immunostimulatory Cytokines to Alum Promotes Enhanced‐Humoral Immunity
Protein antigens are often combined with aluminum hydroxide (alum), the most commonly used adjuvant in licensed vaccines; yet the immunogenicity of alum‐adjuvanted vaccines leaves much room for improvement. Here, the authors demonstrate a strategy for codelivering an immunostimulatory cytokine, the...
Autores principales: | Chang, Jason Y. H., Agarwal, Yash, Rodrigues, Kristen A., Momin, Noor, Ni, Kaiyuan, Read, Benjamin J., Moyer, Tyson J., Mehta, Naveen K., Silva, Murillo, Suh, Heikyung, Melo, Mariane B., Wittrup, K. Dane, Irvine, Darrell J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595138/ https://www.ncbi.nlm.nih.gov/pubmed/36311814 http://dx.doi.org/10.1002/adtp.202100235 |
Ejemplares similares
-
Optimization of an alum-anchored clinical HIV vaccine candidate
por: Rodrigues, Kristen A., et al.
Publicado: (2023) -
Engineered immunogen binding to alum adjuvant enhances humoral immunity
por: Moyer, Tyson J., et al.
Publicado: (2020) -
Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity
por: Agarwal, Yash, et al.
Publicado: (2022) -
Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies
por: Lutz, Emi A., et al.
Publicado: (2022) -
Author Correction: A Engineered immunogen binding to alum adjuvant enhances humoral immunity
por: Moyer, Tyson J., et al.
Publicado: (2020)