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APC/C(Cdc20)-mediated degradation of Clb4 prompts astral microtubule stabilization at anaphase onset

Key for accurate chromosome partitioning to the offspring is the ability of mitotic spindle microtubules to respond to different molecular signals and remodel their dynamics accordingly. Spindle microtubules are conventionally divided into three classes: kinetochore, interpolar, and astral microtubu...

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Detalles Bibliográficos
Autores principales: Zucca, Federico, Visintin, Clara, Li, Jiaming, Gygi, Steven P., Visintin, Rosella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595209/
https://www.ncbi.nlm.nih.gov/pubmed/36269172
http://dx.doi.org/10.1083/jcb.202203089