Stepwise progression of β-selection during T cell development involves histone deacetylation

During T cell development, the first step in creating a unique T cell receptor (TCR) is genetic recombination of the TCRβ chain. The quality of the new TCRβ is assessed at the β-selection checkpoint. Most cells fail this checkpoint and die, but the coordination of fate at the β-selection checkpoint...

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Detalles Bibliográficos
Autores principales: Chann, Anchi S, Charnley, Mirren, Newton, Lucas M, Newbold, Andrea, Wiede, Florian, Tiganis, Tony, Humbert, Patrick O, Johnstone, Ricky W, Russell, Sarah M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595210/
https://www.ncbi.nlm.nih.gov/pubmed/36283704
http://dx.doi.org/10.26508/lsa.202201645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595210/
https://www.ncbi.nlm.nih.gov/pubmed/36283704
http://dx.doi.org/10.26508/lsa.202201645

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