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An NTP-driven mechanism for the nucleotide addition cycle of Escherichia coli RNA polymerase during transcription

The elementary steps of transcription as catalyzed by E. coli RNA polymerase during one and two rounds of the nucleotide addition cycle (NAC) were resolved in rapid kinetic studies. Modelling of stopped-flow kinetic data of pyrophosphate release in a coupled enzyme assay during one round of the NAC...

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Detalles Bibliográficos
Autores principales: Johnson, Ronald S., Strausbauch, Mark, McCloud, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595533/
https://www.ncbi.nlm.nih.gov/pubmed/36282801
http://dx.doi.org/10.1371/journal.pone.0273746