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An NTP-driven mechanism for the nucleotide addition cycle of Escherichia coli RNA polymerase during transcription
The elementary steps of transcription as catalyzed by E. coli RNA polymerase during one and two rounds of the nucleotide addition cycle (NAC) were resolved in rapid kinetic studies. Modelling of stopped-flow kinetic data of pyrophosphate release in a coupled enzyme assay during one round of the NAC...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595533/ https://www.ncbi.nlm.nih.gov/pubmed/36282801 http://dx.doi.org/10.1371/journal.pone.0273746 |