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Multiple immunodominant O-epitopes co-expression in live attenuated Salmonella serovars induce cross-protective immune responses against S. Paratyphi A, S. Typhimurium and S. Enteritidis

Salmonella enterica subsp. enterica (S. enterica) is a significant public health concern and is estimated to cause more than 300,000 deaths annually. Nowadays, the vaccines available for human Salmonellosis prevention are all targeting just one serovar, i.e., S. Typhi, leaving a huge potential risk...

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Detalles Bibliográficos
Autores principales: Li, Pei, Zhang, Ke, Lei, Ting, Zhou, Zuoyong, Luo, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595534/
https://www.ncbi.nlm.nih.gov/pubmed/36228043
http://dx.doi.org/10.1371/journal.pntd.0010866