IL-2–mTORC1 signaling coordinates the STAT1/T-bet axis to ensure Th1 cell differentiation and anti-bacterial immune response in fish

Utilization of specialized Th1 cells to resist intracellular pathogenic infection represents an important innovation of adaptive immunity. Although transcriptional evidence indicates the potential presence of Th1-like cells in some fish species, the existence of CD3(+)CD4(+)IFN-γ(+) T cells, their d...

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Detalles Bibliográficos
Autores principales: Ai, Kete, Li, Kang, Jiao, Xinying, Zhang, Yu, Li, Jiaqi, Zhang, Qian, Wei, Xiumei, Yang, Jialong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595569/
https://www.ncbi.nlm.nih.gov/pubmed/36282845
http://dx.doi.org/10.1371/journal.ppat.1010913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595569/
https://www.ncbi.nlm.nih.gov/pubmed/36282845
http://dx.doi.org/10.1371/journal.ppat.1010913

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