Delivery of the selenoprotein thioredoxin reductase 1 to mammalian cells

Over-expression of genetically encoded thioredoxin reductase 1 (TrxR1) TrxR1 can be toxic to cells due to the formation of a truncated version of the enzyme. We developed a new mammalian cell-based model to investigate TrxR1 activity. Fusion of the HIV-derived cell penetrating peptide (TAT) enabled...

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Detalles Bibliográficos
Autores principales: Wright, David E., Siddika, Tarana, Heinemann, Ilka U., O’Donoghue, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595596/
https://www.ncbi.nlm.nih.gov/pubmed/36304926
http://dx.doi.org/10.3389/fmolb.2022.1031756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595596/
https://www.ncbi.nlm.nih.gov/pubmed/36304926
http://dx.doi.org/10.3389/fmolb.2022.1031756

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