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RGS5: a novel role as a hypoxia-responsive protein that suppresses chemokinetic and chemotactic migration in brain pericytes

Adaptive biological mechanisms to hypoxia are crucial to maintain oxygen homeostasis, especially in the brain. Pericytes, cells uniquely positioned at the blood-brain interface, respond fast to hypoxia by expressing regulator of G-protein signalling 5 (RGS5), a negative regulator of G-protein-couple...

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Detalles Bibliográficos
Autores principales: Enström, Andreas, Carlsson, Robert, Özen, Ilknur, Paul, Gesine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596146/
https://www.ncbi.nlm.nih.gov/pubmed/36111549
http://dx.doi.org/10.1242/bio.059371