Ovariectomy-induced hormone deprivation aggravates Aβ(1-42) deposition in the basolateral amygdala and cholinergic fiber loss in the cortex but not cognitive behavioral symptoms in a triple transgenic mouse model of Alzheimer’s disease

Alzheimer’s disease is the most common type of dementia, being highly prevalent in elderly women. The advanced progression may be due to decreased hormone synthesis during post-menopause as estradiol and progesterone both have neuroprotective potentials. We aimed to confirm that female hormone deple...

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Detalles Bibliográficos
Autores principales: Farkas, Szidónia, Szabó, Adrienn, Török, Bibiána, Sólyomvári, Csenge, Fazekas, Csilla Lea, Bánrévi, Krisztina, Correia, Pedro, Chaves, Tiago, Zelena, Dóra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596151/
https://www.ncbi.nlm.nih.gov/pubmed/36303870
http://dx.doi.org/10.3389/fendo.2022.985424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596151/
https://www.ncbi.nlm.nih.gov/pubmed/36303870
http://dx.doi.org/10.3389/fendo.2022.985424

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