Anopheles homing suppression drive candidates exhibit unexpected performance differences in simulations with spatial structure

Recent experiments have produced several Anopheles gambiae homing gene drives that disrupt female fertility genes, thereby eventually inducing population collapse. Such drives may be highly effective tools to combat malaria. One such homing drive, based on the zpg promoter driving CRISPR/Cas9, was a...

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Detalles Bibliográficos
Autores principales: Champer, Samuel E, Kim, Isabel K, Clark, Andrew G, Messer, Philipp W, Champer, Jackson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Ecology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596161/
https://www.ncbi.nlm.nih.gov/pubmed/36239372
http://dx.doi.org/10.7554/eLife.79121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596161/
https://www.ncbi.nlm.nih.gov/pubmed/36239372
http://dx.doi.org/10.7554/eLife.79121

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